STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRAG1PEAK1 related, kinase-activating pseudokinase 1. (1384 aa)    
Predicted Functional Partners:
RND2
Rho family GTPase 2.
     
 0.663
ENSCAFP00000046000
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
   0.626
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
   0.626
PAX2
Paired box 2.
      
 0.610
ENSCAFP00000047349
Uncharacterized protein.
    
   0.570
CSK
Tyrosine-protein kinase.
    
 
 0.538
MATK
Tyrosine-protein kinase.
    
 
 0.538
RUFY1
RUN and FYVE domain containing 1.
      
 0.473
ZDBF2
Zinc finger DBF-type containing 2.
      
 0.472
KCNJ4
Potassium voltage-gated channel subfamily J member 4.
      
 0.465
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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