PDYN protein (Canis lupus familiaris) - STRING interaction network

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Score

PDYN

Prodynorphin. (256 aa)

Predicted Functional Partners:

OPRM1

0.989

POMC

0.982

PNOC

0.980

OPRD1

0.975

OPRK1

0.964

PENK

0.930

GRIN2B

0.922

GRIN3A

0.915

GRIN2C

0.903

GRIN2A

0.898

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRIN2A	GRIN2B	ENSCAFP00000028005	ENSCAFP00000039796	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	0.999
GRIN2A	GRIN2C	ENSCAFP00000028005	ENSCAFP00000006896	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate ionotropic receptor NMDA type subunit 2C.	0.995
GRIN2A	GRIN3A	ENSCAFP00000028005	ENSCAFP00000003807	Glutamate ionotropic receptor NMDA type subunit 2A.	Glutamate ionotropic receptor NMDA type subunit 3A.	0.969
GRIN2A	PDYN	ENSCAFP00000028005	ENSCAFP00000010070	Glutamate ionotropic receptor NMDA type subunit 2A.	Prodynorphin.	0.898
GRIN2B	GRIN2A	ENSCAFP00000039796	ENSCAFP00000028005	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	Glutamate ionotropic receptor NMDA type subunit 2A.	0.999
GRIN2B	GRIN2C	ENSCAFP00000039796	ENSCAFP00000006896	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	Glutamate ionotropic receptor NMDA type subunit 2C.	0.990
GRIN2B	GRIN3A	ENSCAFP00000039796	ENSCAFP00000003807	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	Glutamate ionotropic receptor NMDA type subunit 3A.	0.983
GRIN2B	PDYN	ENSCAFP00000039796	ENSCAFP00000010070	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	Prodynorphin.	0.922
GRIN2C	GRIN2A	ENSCAFP00000006896	ENSCAFP00000028005	Glutamate ionotropic receptor NMDA type subunit 2C.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.995
GRIN2C	GRIN2B	ENSCAFP00000006896	ENSCAFP00000039796	Glutamate ionotropic receptor NMDA type subunit 2C.	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	0.990
GRIN2C	GRIN3A	ENSCAFP00000006896	ENSCAFP00000003807	Glutamate ionotropic receptor NMDA type subunit 2C.	Glutamate ionotropic receptor NMDA type subunit 3A.	0.911
GRIN2C	PDYN	ENSCAFP00000006896	ENSCAFP00000010070	Glutamate ionotropic receptor NMDA type subunit 2C.	Prodynorphin.	0.903
GRIN3A	GRIN2A	ENSCAFP00000003807	ENSCAFP00000028005	Glutamate ionotropic receptor NMDA type subunit 3A.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.969
GRIN3A	GRIN2B	ENSCAFP00000003807	ENSCAFP00000039796	Glutamate ionotropic receptor NMDA type subunit 3A.	Glutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (By similarity). In concert with DAPK1 at extrasynaptic sites, acts as a central mediator fo [...]	0.983
GRIN3A	GRIN2C	ENSCAFP00000003807	ENSCAFP00000006896	Glutamate ionotropic receptor NMDA type subunit 3A.	Glutamate ionotropic receptor NMDA type subunit 2C.	0.911
GRIN3A	PDYN	ENSCAFP00000003807	ENSCAFP00000010070	Glutamate ionotropic receptor NMDA type subunit 3A.	Prodynorphin.	0.915
OPRD1	OPRK1	ENSCAFP00000017184	ENSCAFP00000041119	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.934
OPRD1	OPRM1	ENSCAFP00000017184	ENSCAFP00000048013	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.969
OPRD1	PDYN	ENSCAFP00000017184	ENSCAFP00000010070	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.	Prodynorphin.	0.975
OPRD1	PENK	ENSCAFP00000017184	ENSCAFP00000010492	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.	Proenkephalin.	0.977