STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC20BCell division cycle 20B. (528 aa)    
Predicted Functional Partners:
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.966
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.963
NEK2
NIMA related kinase 2.
   
 
 0.949
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 
 0.944
UBE2C
Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.936
ENSCAFP00000059003
Uncharacterized protein.
   
 
 0.936
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
 
 0.935
CDCA3
Cell division cycle associated 3.
   
 
 0.922
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.919
CDCA8
Cell division cycle associated 8.
   
 
 0.918
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.