GSX1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

GSX1

GS homeobox 1. (353 aa)

Predicted Functional Partners:

VRK2

0.691

ASCL1

0.680

GSX2

0.629

SP9

0.571

PROKR1

0.528

ASCL2

0.502

FANCL

0.498

SP8

0.489

OLIG3

0.460

OLIG2

0.422

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	GSX1	ENSCAFP00000010864	ENSCAFP00000010073	Achaete-scute family bHLH transcription factor 1.	GS homeobox 1.	0.680
ASCL1	OLIG2	ENSCAFP00000010864	ENSCAFP00000041269	Achaete-scute family bHLH transcription factor 1.	Oligodendrocyte transcription factor 2.	0.790
ASCL1	SP9	ENSCAFP00000010864	ENSCAFP00000019432	Achaete-scute family bHLH transcription factor 1.	Sp9 transcription factor.	0.500
ASCL2	GSX1	ENSCAFP00000014850	ENSCAFP00000010073	Achaete-scute family bHLH transcription factor 2.	GS homeobox 1.	0.502
FANCL	GSX1	ENSCAFP00000044110	ENSCAFP00000010073	FA complementation group L.	GS homeobox 1.	0.498
FANCL	GSX2	ENSCAFP00000044110	ENSCAFP00000003023	FA complementation group L.	GS homeobox 2.	0.428
FANCL	VRK2	ENSCAFP00000044110	ENSCAFP00000042668	FA complementation group L.	VRK serine/threonine kinase 2.	0.618
GSX1	ASCL1	ENSCAFP00000010073	ENSCAFP00000010864	GS homeobox 1.	Achaete-scute family bHLH transcription factor 1.	0.680
GSX1	ASCL2	ENSCAFP00000010073	ENSCAFP00000014850	GS homeobox 1.	Achaete-scute family bHLH transcription factor 2.	0.502
GSX1	FANCL	ENSCAFP00000010073	ENSCAFP00000044110	GS homeobox 1.	FA complementation group L.	0.498
GSX1	GSX2	ENSCAFP00000010073	ENSCAFP00000003023	GS homeobox 1.	GS homeobox 2.	0.629
GSX1	OLIG2	ENSCAFP00000010073	ENSCAFP00000041269	GS homeobox 1.	Oligodendrocyte transcription factor 2.	0.422
GSX1	OLIG3	ENSCAFP00000010073	ENSCAFP00000000380	GS homeobox 1.	Oligodendrocyte transcription factor 3.	0.460
GSX1	PROKR1	ENSCAFP00000010073	ENSCAFP00000041975	GS homeobox 1.	Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.528
GSX1	SP8	ENSCAFP00000010073	ENSCAFP00000044124	GS homeobox 1.	Uncharacterized protein.	0.489
GSX1	SP9	ENSCAFP00000010073	ENSCAFP00000019432	GS homeobox 1.	Sp9 transcription factor.	0.571
GSX1	VRK2	ENSCAFP00000010073	ENSCAFP00000042668	GS homeobox 1.	VRK serine/threonine kinase 2.	0.691
GSX2	FANCL	ENSCAFP00000003023	ENSCAFP00000044110	GS homeobox 2.	FA complementation group L.	0.428
GSX2	GSX1	ENSCAFP00000003023	ENSCAFP00000010073	GS homeobox 2.	GS homeobox 1.	0.629
GSX2	VRK2	ENSCAFP00000003023	ENSCAFP00000042668	GS homeobox 2.	VRK serine/threonine kinase 2.	0.626