STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRPAUncharacterized protein. (506 aa)    
Predicted Functional Partners:
CD47
CD47 molecule.
   
 0.994
SYK
Tyrosine-protein kinase.
   
 0.909
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.583
GRB2
Growth factor receptor bound protein 2.
   
 0.574
LOC478984
Uncharacterized protein.
   
 
 0.555
FYB1
FYN binding protein 1.
   
 
 0.540
SKAP2
Src kinase associated phosphoprotein 2.
   
 
 0.529
RPS27
40S ribosomal protein S27.
      
 0.519
RPS27L-2
40S ribosomal protein S27.
      
 0.495
ENSCAFP00000059444
Uncharacterized protein.
      
 0.495
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.