STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPHS1NPHS1 adhesion molecule, nephrin. (1295 aa)    
Predicted Functional Partners:
NPHS2
NPHS2 stomatin family member, podocin.
   
 
 0.942
KIRREL1
Kirre like nephrin family adhesion molecule 1.
   
0.919
KIRREL2
Kirre like nephrin family adhesion molecule 2.
   
0.918
KIRREL3
Kirre like nephrin family adhesion molecule 3.
   
0.918
CD2AP
CD2 associated protein.
    
 
 0.867
WT1
WT1 transcription factor.
    
 
 0.854
SYNPO
Synaptopodin.
   
  
 0.759
NCK1
Cytoplasmic protein.
    
 0.753
NCK2
Cytoplasmic protein.
    
 0.720
FYN
Tyrosine-protein kinase.
   
 0.713
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.