STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1930 aa)    
Predicted Functional Partners:
B3GLCT
Beta 3-glucosyltransferase.
    
 0.745
POFUT2
Protein O-fucosyltransferase 2.
     
 0.691
ZCCHC24
Zinc finger CCHC-type containing 24.
   
  
 0.593
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12.
   
  
 0.591
TM4SF1
Transmembrane 4 L six family member 1.
   
  
 0.567
ACAN
Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
   
  
 0.567
NOSTRIN
Nitric oxide synthase trafficking.
   
  
 0.564
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
      
 0.560
ZNF608
Zinc finger protein 608.
      
 0.527
CCDC102A
Coiled-coil domain containing 102A.
      
 0.523
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.