Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC52A3Solute carrier family 52 member 3. (469 aa)    
Predicted Functional Partners:
SLC38A6
Solute carrier family 38 member 6.
      
 0.792
SLC17A8
Solute carrier family 17 member 8.
      
 0.756
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.720
SLC35C2
Solute carrier family 35 member C2.
   
  
 0.700
SLC41A2
Solute carrier family 41 member 2.
      
 0.623
WFS1
Wolframin ER transmembrane glycoprotein.
      
 0.580
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
      
 0.567
COCH
Cochlin.
      
 0.566
PLCE1
Phosphoinositide phospholipase C.
      
 0.559
TMC1
Transmembrane channel-like protein.
      
 0.541
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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