TRIB3 protein (Canis lupus familiaris) - STRING interaction network

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Score

TRIB3

Tribbles pseudokinase 3. (358 aa)

Predicted Functional Partners:

COP1

0.955

AKT3

0.936

STK40

0.932

AKT1

0.929

PPARA

0.923

ATF4

0.920

AKT2

0.853

CHAC1

0.820

SQSTM1

0.801

ASNS

0.800

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSCAFP00000027133	ENSCAFP00000023241	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.787
AKT1	ATF4	ENSCAFP00000027133	ENSCAFP00000001900	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Activating transcription factor 4.	0.831
AKT1	PPARA	ENSCAFP00000027133	ENSCAFP00000054067	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Peroxisome proliferator-activated receptor alpha; Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn- glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and [...]	0.405
AKT1	TRIB3	ENSCAFP00000027133	ENSCAFP00000010352	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tribbles pseudokinase 3.	0.929
AKT2	ATF4	ENSCAFP00000008032	ENSCAFP00000001900	AKT serine/threonine kinase 2.	Activating transcription factor 4.	0.642
AKT2	PPARA	ENSCAFP00000008032	ENSCAFP00000054067	AKT serine/threonine kinase 2.	Peroxisome proliferator-activated receptor alpha; Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn- glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and [...]	0.429
AKT2	TRIB3	ENSCAFP00000008032	ENSCAFP00000010352	AKT serine/threonine kinase 2.	Tribbles pseudokinase 3.	0.853
AKT3	AKT1	ENSCAFP00000023241	ENSCAFP00000027133	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.787
AKT3	ATF4	ENSCAFP00000023241	ENSCAFP00000001900	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Activating transcription factor 4.	0.805
AKT3	TRIB3	ENSCAFP00000023241	ENSCAFP00000010352	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tribbles pseudokinase 3.	0.936
ASNS	ATF4	ENSCAFP00000003236	ENSCAFP00000001900	Asparagine synthetase [glutamine-hydrolyzing].	Activating transcription factor 4.	0.706
ASNS	CHAC1	ENSCAFP00000003236	ENSCAFP00000013862	Asparagine synthetase [glutamine-hydrolyzing].	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.766
ASNS	TRIB3	ENSCAFP00000003236	ENSCAFP00000010352	Asparagine synthetase [glutamine-hydrolyzing].	Tribbles pseudokinase 3.	0.800
ATF4	AKT1	ENSCAFP00000001900	ENSCAFP00000027133	Activating transcription factor 4.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.831
ATF4	AKT2	ENSCAFP00000001900	ENSCAFP00000008032	Activating transcription factor 4.	AKT serine/threonine kinase 2.	0.642
ATF4	AKT3	ENSCAFP00000001900	ENSCAFP00000023241	Activating transcription factor 4.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.805
ATF4	ASNS	ENSCAFP00000001900	ENSCAFP00000003236	Activating transcription factor 4.	Asparagine synthetase [glutamine-hydrolyzing].	0.706
ATF4	CHAC1	ENSCAFP00000001900	ENSCAFP00000013862	Activating transcription factor 4.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.570
ATF4	TRIB3	ENSCAFP00000001900	ENSCAFP00000010352	Activating transcription factor 4.	Tribbles pseudokinase 3.	0.920
CHAC1	ASNS	ENSCAFP00000013862	ENSCAFP00000003236	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Asparagine synthetase [glutamine-hydrolyzing].	0.766