SOX12 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SOX12

Transcription factor SOX. (321 aa)

Predicted Functional Partners:

GYG1

0.657

COL5A3

0.603

SOX5

0.568

CAPN5

0.541

SOX13

0.502

PRDM1

0.495

TCF7

0.495

CHCHD6

0.493

GYS1

0.490

GYS2

0.490

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPN5	SOX12	ENSCAFP00000062879	ENSCAFP00000010358	Calpain 5; Belongs to the peptidase C2 family.	Transcription factor SOX.	0.541
CHCHD6	SOX12	ENSCAFP00000058117	ENSCAFP00000010358	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	Transcription factor SOX.	0.493
COL5A3	SOX12	ENSCAFP00000026524	ENSCAFP00000010358	Collagen type V alpha 3 chain.	Transcription factor SOX.	0.603
GYG1	GYS1	ENSCAFP00000056135	ENSCAFP00000005745	Glycogenin 1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.998
GYG1	GYS2	ENSCAFP00000056135	ENSCAFP00000018019	Glycogenin 1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.987
GYG1	SOX12	ENSCAFP00000056135	ENSCAFP00000010358	Glycogenin 1.	Transcription factor SOX.	0.657
GYS1	GYG1	ENSCAFP00000005745	ENSCAFP00000056135	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	Glycogenin 1.	0.998
GYS1	GYS2	ENSCAFP00000005745	ENSCAFP00000018019	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.881
GYS1	SOX12	ENSCAFP00000005745	ENSCAFP00000010358	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	Transcription factor SOX.	0.490
GYS2	GYG1	ENSCAFP00000018019	ENSCAFP00000056135	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	Glycogenin 1.	0.987
GYS2	GYS1	ENSCAFP00000018019	ENSCAFP00000005745	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.881
GYS2	SOX12	ENSCAFP00000018019	ENSCAFP00000010358	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	Transcription factor SOX.	0.490
PRDM1	SOX12	ENSCAFP00000005506	ENSCAFP00000010358	PR/SET domain 1.	Transcription factor SOX.	0.495
PRDM1	TCF7	ENSCAFP00000005506	ENSCAFP00000043629	PR/SET domain 1.	Transcription factor 7.	0.402
SOX12	CAPN5	ENSCAFP00000010358	ENSCAFP00000062879	Transcription factor SOX.	Calpain 5; Belongs to the peptidase C2 family.	0.541
SOX12	CHCHD6	ENSCAFP00000010358	ENSCAFP00000058117	Transcription factor SOX.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.493
SOX12	COL5A3	ENSCAFP00000010358	ENSCAFP00000026524	Transcription factor SOX.	Collagen type V alpha 3 chain.	0.603
SOX12	GYG1	ENSCAFP00000010358	ENSCAFP00000056135	Transcription factor SOX.	Glycogenin 1.	0.657
SOX12	GYS1	ENSCAFP00000010358	ENSCAFP00000005745	Transcription factor SOX.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.490
SOX12	GYS2	ENSCAFP00000010358	ENSCAFP00000018019	Transcription factor SOX.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.490