STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB129Beta-defensin 129. (166 aa)    
Predicted Functional Partners:
DEFB121
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.854
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.853
DEFB125
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.824
SPAG11B
Sperm-associated antigen 11 variant C.
      
 0.814
DEFB126
Beta-defensin 141.
      
 0.786
DEFB116
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.764
DEFB119
Beta-defensin 119; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.713
DEFB127
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.675
DEFB110
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.654
DEFB118
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.608
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.