STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEFB127Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (100 aa)    
Predicted Functional Partners:
DCTN6
Dynactin subunit 6.
    
   0.828
DCTN5
Dynactin subunit 5.
    
   0.827
ACTR10
Actin related protein 10; Belongs to the actin family.
    
 
 0.810
DCTN4
Dynactin subunit 4.
    
   0.801
DCTN3
Dynactin subunit 3.
    
   0.779
ACTR1A
Alpha-centractin; Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.
    
 
 0.669
ACTR1B
Actin related protein 1B.
    
 
 0.669
DEFB125
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.620
DEFB134
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.615
DEFB129
Beta-defensin 129.
   
  
 0.583
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.