STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)    
Predicted Functional Partners:
ARFIP2
ADP ribosylation factor interacting protein 2.
    
 0.954
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
   
  
 0.923
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 
 0.914
GOLGA4
Golgin A4.
    
 0.870
RAB6A
RAB6A, member RAS oncogene family.
   
 0.838
RAB6B
RAB6B, member RAS oncogene family.
   
 0.836
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
    
 
 0.814
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 0.787
SCOC
Short coiled-coil protein.
   
 
 0.772
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2.
   
 
 0.766
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.