STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRIP3Nuclear receptor interacting protein 3. (239 aa)    
Predicted Functional Partners:
TBC1D30
TBC1 domain family member 30.
    
 
 0.694
RTF2
Replication termination factor 2.
      
 0.692
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.691
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.658
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 
 0.658
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
      
 0.629
DDI1
DNA damage inducible 1 homolog 1.
   
 
 0.625
DDI2
Uncharacterized protein.
   
 
 0.625
PSMD4
Proteasome 26S subunit, non-ATPase 4.
   
 
 0.621
ENSCAFP00000065754
VWFA domain-containing protein.
   
 
 0.621
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]