STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)    
Predicted Functional Partners:
TMEM30A
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 
 0.823
LOC487951
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 
 0.612
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
   
 
 0.568
PWP1
PWP1 homolog, endonuclein.
      
 0.567
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1.
      
 0.564
ATP1B3
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
 
 0.532
XPNPEP1
X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.
   
 
 0.522
CCDC73
Coiled-coil domain containing 73.
      
 0.517
COG1
Component of oligomeric golgi complex 1.
      
 0.504
MYO16
Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.501
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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