STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESPL1Extra spindle pole bodies like 1, separase. (2108 aa)    
Predicted Functional Partners:
PTTG1
Uncharacterized protein.
   
 0.998
SMC3
Structural maintenance of chromosomes protein.
   
 0.989
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
  
 
 0.982
RAD21
RAD21 cohesin complex component.
   
 0.979
REC8
REC8 meiotic recombination protein.
   
 0.978
SMC1A
Structural maintenance of chromosomes protein.
   
 0.971
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.968
SMC1B
Structural maintenance of chromosomes protein.
   
 0.967
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.964
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.958
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.