STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESPL1Extra spindle pole bodies like 1, separase. (2108 aa)    
Predicted Functional Partners:
PTTG1
Uncharacterized protein.
   
 0.999
PLK1
Serine/threonine-protein kinase PLK.
   
 0.996
SMC3
Structural maintenance of chromosomes protein.
   
 0.996
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.993
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
  
 
 0.977
RAD21
RAD21 cohesin complex component.
   
 0.973
REC8
REC8 meiotic recombination protein.
   
 0.972
SMC1A
Structural maintenance of chromosomes protein.
   
 0.962
CDC20
Cell division cycle 20.
   
 0.955
SMC1B
Structural maintenance of chromosomes protein.
   
 0.953
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.