NAT10 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

NAT10

RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1025 aa)

Predicted Functional Partners:

NOL10

0.993

AATF

0.992

NOP58

0.988

RRP12

0.986

BMS1

0.984

WDR36

0.983

PDCD11

0.983

DKC1

0.983

PWP2

0.983

UTP20

0.980

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AATF	BMS1	ENSCAFP00000036644	ENSCAFP00000010578	Apoptosis antagonizing transcription factor.	BMS1 ribosome biogenesis factor.	0.958
AATF	DKC1	ENSCAFP00000036644	ENSCAFP00000029020	Apoptosis antagonizing transcription factor.	Dyskerin pseudouridine synthase 1.	0.794
AATF	NAT10	ENSCAFP00000036644	ENSCAFP00000010456	Apoptosis antagonizing transcription factor.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.992
AATF	NOL10	ENSCAFP00000036644	ENSCAFP00000064542	Apoptosis antagonizing transcription factor.	Nucleolar protein 10.	0.987
AATF	NOP58	ENSCAFP00000036644	ENSCAFP00000018346	Apoptosis antagonizing transcription factor.	NOP58 ribonucleoprotein.	0.950
AATF	PDCD11	ENSCAFP00000036644	ENSCAFP00000015340	Apoptosis antagonizing transcription factor.	Programmed cell death 11.	0.942
AATF	PWP2	ENSCAFP00000036644	ENSCAFP00000062521	Apoptosis antagonizing transcription factor.	Uncharacterized protein.	0.904
AATF	RRP12	ENSCAFP00000036644	ENSCAFP00000013310	Apoptosis antagonizing transcription factor.	Ribosomal RNA processing 12 homolog.	0.807
AATF	UTP20	ENSCAFP00000036644	ENSCAFP00000010364	Apoptosis antagonizing transcription factor.	UTP20 small subunit processome component.	0.876
AATF	WDR36	ENSCAFP00000036644	ENSCAFP00000010969	Apoptosis antagonizing transcription factor.	WD repeat domain 36.	0.927
BMS1	AATF	ENSCAFP00000010578	ENSCAFP00000036644	BMS1 ribosome biogenesis factor.	Apoptosis antagonizing transcription factor.	0.958
BMS1	DKC1	ENSCAFP00000010578	ENSCAFP00000029020	BMS1 ribosome biogenesis factor.	Dyskerin pseudouridine synthase 1.	0.686
BMS1	NAT10	ENSCAFP00000010578	ENSCAFP00000010456	BMS1 ribosome biogenesis factor.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.984
BMS1	NOL10	ENSCAFP00000010578	ENSCAFP00000064542	BMS1 ribosome biogenesis factor.	Nucleolar protein 10.	0.981
BMS1	NOP58	ENSCAFP00000010578	ENSCAFP00000018346	BMS1 ribosome biogenesis factor.	NOP58 ribonucleoprotein.	0.968
BMS1	PDCD11	ENSCAFP00000010578	ENSCAFP00000015340	BMS1 ribosome biogenesis factor.	Programmed cell death 11.	0.986
BMS1	PWP2	ENSCAFP00000010578	ENSCAFP00000062521	BMS1 ribosome biogenesis factor.	Uncharacterized protein.	0.978
BMS1	RRP12	ENSCAFP00000010578	ENSCAFP00000013310	BMS1 ribosome biogenesis factor.	Ribosomal RNA processing 12 homolog.	0.975
BMS1	UTP20	ENSCAFP00000010578	ENSCAFP00000010364	BMS1 ribosome biogenesis factor.	UTP20 small subunit processome component.	0.985
BMS1	WDR36	ENSCAFP00000010578	ENSCAFP00000010969	BMS1 ribosome biogenesis factor.	WD repeat domain 36.	0.987

page 1 of 6

Server load: low (40%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About