node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBS | CDKN1B | ENSCAFP00000040348 | ENSCAFP00000019502 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | 0.690 |
CBS | EIF2AK3 | ENSCAFP00000040348 | ENSCAFP00000010977 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Eukaryotic translation initiation factor 2 alpha kinase 3. | 0.699 |
CBS | FBN1 | ENSCAFP00000040348 | ENSCAFP00000021725 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Uncharacterized protein. | 0.653 |
CBS | GPC3 | ENSCAFP00000040348 | ENSCAFP00000027825 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | 0.682 |
CBS | GRB10 | ENSCAFP00000040348 | ENSCAFP00000005101 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Growth factor receptor bound protein 10. | 0.704 |
CBS | OBSL1 | ENSCAFP00000040348 | ENSCAFP00000039377 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Obscurin like 1. | 0.699 |
CBS | PLAG1 | ENSCAFP00000040348 | ENSCAFP00000010477 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PLAG1 zinc finger. | 0.762 |
CDKN1B | CBS | ENSCAFP00000019502 | ENSCAFP00000040348 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.690 |
CDKN1B | EIF2AK3 | ENSCAFP00000019502 | ENSCAFP00000010977 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | Eukaryotic translation initiation factor 2 alpha kinase 3. | 0.785 |
CDKN1B | FBN1 | ENSCAFP00000019502 | ENSCAFP00000021725 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | Uncharacterized protein. | 0.732 |
CDKN1B | GPC3 | ENSCAFP00000019502 | ENSCAFP00000027825 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | 0.795 |
CDKN1B | GRB10 | ENSCAFP00000019502 | ENSCAFP00000005101 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | Growth factor receptor bound protein 10. | 0.737 |
CDKN1B | OBSL1 | ENSCAFP00000019502 | ENSCAFP00000039377 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | Obscurin like 1. | 0.677 |
CDKN1B | PLAG1 | ENSCAFP00000019502 | ENSCAFP00000010477 | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | PLAG1 zinc finger. | 0.770 |
CHCHD7 | IMPAD1 | ENSCAFP00000010480 | ENSCAFP00000010505 | Coiled-coil-helix-coiled-coil-helix domain containing 7. | Inositol monophosphatase domain containing 1. | 0.813 |
CHCHD7 | LCORL | ENSCAFP00000010480 | ENSCAFP00000046152 | Coiled-coil-helix-coiled-coil-helix domain containing 7. | Ligand dependent nuclear receptor corepressor like. | 0.582 |
CHCHD7 | PLAG1 | ENSCAFP00000010480 | ENSCAFP00000010477 | Coiled-coil-helix-coiled-coil-helix domain containing 7. | PLAG1 zinc finger. | 0.879 |
EIF2AK3 | CBS | ENSCAFP00000010977 | ENSCAFP00000040348 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.699 |
EIF2AK3 | CDKN1B | ENSCAFP00000010977 | ENSCAFP00000019502 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. | 0.785 |
EIF2AK3 | FBN1 | ENSCAFP00000010977 | ENSCAFP00000021725 | Eukaryotic translation initiation factor 2 alpha kinase 3. | Uncharacterized protein. | 0.729 |