STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSRLipolysis stimulated lipoprotein receptor. (647 aa)    
Predicted Functional Partners:
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1.
   
  
 0.697
CLMN
Calmin.
   
  
 0.595
A1CF
APOBEC1 complementation factor.
      
 0.592
PBLD
Phenazine biosynthesis like protein domain containing.
      
 0.534
CLMP
CXADR like membrane protein.
      
 0.518
TJP2
Tight junction protein ZO-2; Plays a role in tight junctions and adherens junctions; Belongs to the MAGUK family.
   
 
 0.498
CLDN7
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.493
IL17RC
Interleukin 17 receptor C.
   
    0.489
CTRB2
Chymotrypsin 2 chain A; Belongs to the peptidase S1 family.
    
 0.481
LOC479649
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.481
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.