SPATA13 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

SPATA13

Uncharacterized protein. (1331 aa)

Predicted Functional Partners:

APC

0.976

APC2

0.952

RAC2

0.915

RAC1

0.901

ARHGEF4-2

0.865

RAC3

0.835

CDC42-2

0.828

ARHGEF4

0.786

ENSCAFP00000046000

0.779

YWHAE

0.779

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC	APC2	ENSCAFP00000048524	ENSCAFP00000028862	APC regulator of WNT signaling pathway.	APC regulator of WNT signaling pathway 2.	0.995
APC	ARHGEF4	ENSCAFP00000048524	ENSCAFP00000006261	APC regulator of WNT signaling pathway.	Rho guanine nucleotide exchange factor 4.	0.960
APC	ARHGEF4-2	ENSCAFP00000048524	ENSCAFP00000046529	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.960
APC	CDC42-2	ENSCAFP00000048524	ENSCAFP00000060180	APC regulator of WNT signaling pathway.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.597
APC	SPATA13	ENSCAFP00000048524	ENSCAFP00000010557	APC regulator of WNT signaling pathway.	Uncharacterized protein.	0.976
APC2	APC	ENSCAFP00000028862	ENSCAFP00000048524	APC regulator of WNT signaling pathway 2.	APC regulator of WNT signaling pathway.	0.995
APC2	ARHGEF4	ENSCAFP00000028862	ENSCAFP00000006261	APC regulator of WNT signaling pathway 2.	Rho guanine nucleotide exchange factor 4.	0.904
APC2	ARHGEF4-2	ENSCAFP00000028862	ENSCAFP00000046529	APC regulator of WNT signaling pathway 2.	Uncharacterized protein.	0.904
APC2	SPATA13	ENSCAFP00000028862	ENSCAFP00000010557	APC regulator of WNT signaling pathway 2.	Uncharacterized protein.	0.952
ARHGEF4	APC	ENSCAFP00000006261	ENSCAFP00000048524	Rho guanine nucleotide exchange factor 4.	APC regulator of WNT signaling pathway.	0.960
ARHGEF4	APC2	ENSCAFP00000006261	ENSCAFP00000028862	Rho guanine nucleotide exchange factor 4.	APC regulator of WNT signaling pathway 2.	0.904
ARHGEF4	CDC42-2	ENSCAFP00000006261	ENSCAFP00000060180	Rho guanine nucleotide exchange factor 4.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.712
ARHGEF4	RAC1	ENSCAFP00000006261	ENSCAFP00000032062	Rho guanine nucleotide exchange factor 4.	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	0.721
ARHGEF4	RAC2	ENSCAFP00000006261	ENSCAFP00000002174	Rho guanine nucleotide exchange factor 4.	Rac family small GTPase 2.	0.835
ARHGEF4	RAC3	ENSCAFP00000006261	ENSCAFP00000008868	Rho guanine nucleotide exchange factor 4.	Uncharacterized protein.	0.709
ARHGEF4	SPATA13	ENSCAFP00000006261	ENSCAFP00000010557	Rho guanine nucleotide exchange factor 4.	Uncharacterized protein.	0.786
ARHGEF4-2	APC	ENSCAFP00000046529	ENSCAFP00000048524	Uncharacterized protein.	APC regulator of WNT signaling pathway.	0.960
ARHGEF4-2	APC2	ENSCAFP00000046529	ENSCAFP00000028862	Uncharacterized protein.	APC regulator of WNT signaling pathway 2.	0.904
ARHGEF4-2	CDC42-2	ENSCAFP00000046529	ENSCAFP00000060180	Uncharacterized protein.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.820
ARHGEF4-2	RAC1	ENSCAFP00000046529	ENSCAFP00000032062	Uncharacterized protein.	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	0.825