STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI4Leucine rich repeat LGI family member 4. (534 aa)    
Predicted Functional Partners:
ADAM22
ADAM metallopeptidase domain 22.
   
 
 0.969
ADAM11
ADAM metallopeptidase domain 11.
     
 0.836
ADGRG6
Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family.
      
 0.719
NAB1
NGFI-A binding protein 1.
   
  
 0.595
ADAM23
ADAM metallopeptidase domain 23.
      
 0.593
PLEKHG2
Pleckstrin homology and RhoGEF domain containing G2.
      
 0.553
MECR
Mitochondrial trans-2-enoyl-CoA reductase.
      
 0.495
MYOT
Myotilin.
      
 0.493
DUSP21
Dual specificity phosphatase 21; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.491
PUS1
Pseudouridine synthase 1.
   
  
 0.487
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.