Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAPRIN1Uncharacterized protein. (717 aa)    
Predicted Functional Partners:
G3BP1
G3BP stress granule assembly factor 1.
   
 
 0.984
G3BP2
G3BP stress granule assembly factor 2.
   
 
 0.978
FXR1
FMR1 autosomal homolog 1.
   
 
 0.943
FXR2
FMR1 autosomal homolog 2.
   
 
 0.915
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.910
FMR1
Fragile X mental retardation 1.
   
 
 0.847
TIA1
TIA1 cytotoxic granule associated RNA binding protein.
   
 
 0.846
STAU1
Staufen double-stranded RNA binding protein 1.
   
 
 0.791
NUFIP2
Nuclear FMR1 interacting protein 2.
    
 
 0.786
YTHDF1
YTH N6-methyladenosine RNA binding protein 1.
   
 
 0.784
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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