STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA8Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family. (290 aa)    
Predicted Functional Partners:
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 
 0.835
ZNF236
Zinc finger protein 236.
      
 0.665
HSD17B14
Hydroxysteroid 17-beta dehydrogenase 14.
   
   0.596
RPF2
Ribosome production factor 2 homolog.
   
 
 0.582
VLDLR
Uncharacterized protein.
   
  
 0.570
CYP24A1
Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.542
SLC26A3
Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
   
 
 0.537
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.507
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
    
 
 0.497
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
    
 
 0.497
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.