STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACSSacsin molecular chaperone. (4561 aa)    
Predicted Functional Partners:
ZKSCAN8
Zinc finger with KRAB and SCAN domains 8.
    
 
 0.722
OTUD4
OTU deubiquitinase 4.
   
  
 0.720
ZBTB41
Zinc finger and BTB domain containing 41.
   
 
 0.712
RNF216
Ring finger protein 216.
   
 
 0.702
GAN
Gigaxonin.
    
 
 0.686
SHC2
Uncharacterized protein.
      
 0.653
INCENP
Inner centromere protein.
   
 
 0.638
TEX15
Testis expressed 15, meiosis and synapsis associated.
    
 
 0.637
SNX11
Sorting nexin 11.
    
 
 0.618
EMP3
Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family.
   
  
 0.609
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.