GGH protein (Canis lupus familiaris) - STRING interaction network

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Score

GGH

Folate gamma-glutamyl hydrolase. (301 aa)

Predicted Functional Partners:

FPGS

0.969

TCAP

0.780

DHFR

0.760

LOC609048

0.753

SLC19A1

0.747

UGDH

0.709

TPMT

0.702

PEX7

0.692

TYMS

0.634

ENSCAFP00000045150

0.629

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR	FPGS	ENSCAFP00000036312	ENSCAFP00000029808	DHFR domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.874
DHFR	GGH	ENSCAFP00000036312	ENSCAFP00000010704	DHFR domain-containing protein.	Folate gamma-glutamyl hydrolase.	0.760
DHFR	TPMT	ENSCAFP00000036312	ENSCAFP00000014924	DHFR domain-containing protein.	Thiopurine S-methyltransferase.	0.425
DHFR	TYMS	ENSCAFP00000036312	ENSCAFP00000027096	DHFR domain-containing protein.	Thymidylate synthetase.	0.972
ENSCAFP00000045150	FPGS	ENSCAFP00000045150	ENSCAFP00000029808	DHFR domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.705
ENSCAFP00000045150	GGH	ENSCAFP00000045150	ENSCAFP00000010704	DHFR domain-containing protein.	Folate gamma-glutamyl hydrolase.	0.629
ENSCAFP00000045150	TYMS	ENSCAFP00000045150	ENSCAFP00000027096	DHFR domain-containing protein.	Thymidylate synthetase.	0.817
FPGS	DHFR	ENSCAFP00000029808	ENSCAFP00000036312	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	DHFR domain-containing protein.	0.874
FPGS	ENSCAFP00000045150	ENSCAFP00000029808	ENSCAFP00000045150	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	DHFR domain-containing protein.	0.705
FPGS	GGH	ENSCAFP00000029808	ENSCAFP00000010704	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Folate gamma-glutamyl hydrolase.	0.969
FPGS	LOC609048	ENSCAFP00000029808	ENSCAFP00000038964	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.874
FPGS	SLC19A1	ENSCAFP00000029808	ENSCAFP00000017520	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Solute carrier family 19 member 1.	0.436
FPGS	TYMS	ENSCAFP00000029808	ENSCAFP00000027096	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Thymidylate synthetase.	0.847
GGH	DHFR	ENSCAFP00000010704	ENSCAFP00000036312	Folate gamma-glutamyl hydrolase.	DHFR domain-containing protein.	0.760
GGH	ENSCAFP00000045150	ENSCAFP00000010704	ENSCAFP00000045150	Folate gamma-glutamyl hydrolase.	DHFR domain-containing protein.	0.629
GGH	FPGS	ENSCAFP00000010704	ENSCAFP00000029808	Folate gamma-glutamyl hydrolase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.969
GGH	LOC609048	ENSCAFP00000010704	ENSCAFP00000038964	Folate gamma-glutamyl hydrolase.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.753
GGH	PEX7	ENSCAFP00000010704	ENSCAFP00000000364	Folate gamma-glutamyl hydrolase.	Peroxisomal biogenesis factor 7.	0.692
GGH	SLC19A1	ENSCAFP00000010704	ENSCAFP00000017520	Folate gamma-glutamyl hydrolase.	Solute carrier family 19 member 1.	0.747
GGH	TCAP	ENSCAFP00000010704	ENSCAFP00000044397	Folate gamma-glutamyl hydrolase.	Titin-cap.	0.780