STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM3DFamily with sequence similarity 3 member D. (224 aa)    
Predicted Functional Partners:
CLCA4
Chloride channel accessory 4.
   
  
 0.697
SCEL
Sciellin.
      
 0.597
KRT3
Keratin 3; Belongs to the intermediate filament family.
      
 0.591
PRF1
Perforin 1.
      
 0.510
MGAT1
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase.
     
 0.508
TXK
Tyrosine-protein kinase.
   
  
 0.490
VSIG2
V-set and immunoglobulin domain containing 2.
   
  
 0.485
HSPB8
Heat shock protein beta-8; Displays temperature-dependent chaperone activity. Belongs to the small heat shock protein (HSP20) family.
      
 0.482
IL12RB2
Interleukin 12 receptor subunit beta 2.
      
 0.430
DUOX2
Dual oxidase 2.
      
 0.427
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.