STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT6BKeratin 75; Belongs to the intermediate filament family. (565 aa)    
Predicted Functional Partners:
LOC482175
Transmembrane protease serine; Belongs to the peptidase S1 family.
   
 
 0.822
KRT13
IF rod domain-containing protein; Belongs to the intermediate filament family.
  
0.802
KRT26
IF rod domain-containing protein; Belongs to the intermediate filament family.
  
0.657
KRT25
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
0.652
KRT10
Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin; Belongs to the intermediate filament family.
   
0.639
KRT9
Keratin, type I cytoskeletal 9; May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly (By similarity).
   
0.637
KRT33A
IF rod domain-containing protein; Belongs to the intermediate filament family.
  
0.625
KRT18
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
0.622
KRT12
Keratin 12; Belongs to the intermediate filament family.
  
0.616
KRT31
IF rod domain-containing protein; Belongs to the intermediate filament family.
  
0.615
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.