| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CNGB3 | GNB3 | ENSCAFP00000013075 | ENSCAFP00000058821 | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.738 |
| CNGB3 | GNB5 | ENSCAFP00000013075 | ENSCAFP00000023022 | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | G protein subunit beta 5. | 0.538 |
| CNGB3 | LRIT3 | ENSCAFP00000013075 | ENSCAFP00000016927 | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | Leucine rich repeat, Ig-like and transmembrane domains 3. | 0.527 |
| CNGB3 | RGS11 | ENSCAFP00000013075 | ENSCAFP00000060980 | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | Regulator of G protein signaling 11. | 0.546 |
| CNGB3 | RGS7BP | ENSCAFP00000013075 | ENSCAFP00000010809 | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | Regulator of G protein signaling 7 binding protein. | 0.623 |
| CNGB3 | RGS9BP | ENSCAFP00000013075 | ENSCAFP00000011151 | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | Regulator of G protein signaling 9 binding protein. | 0.698 |
| GNB3 | CNGB3 | ENSCAFP00000058821 | ENSCAFP00000013075 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | 0.738 |
| GNB3 | GNB5 | ENSCAFP00000058821 | ENSCAFP00000023022 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | G protein subunit beta 5. | 0.839 |
| GNB3 | LRIT3 | ENSCAFP00000058821 | ENSCAFP00000016927 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Leucine rich repeat, Ig-like and transmembrane domains 3. | 0.402 |
| GNB3 | RGS11 | ENSCAFP00000058821 | ENSCAFP00000060980 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Regulator of G protein signaling 11. | 0.841 |
| GNB3 | RGS6 | ENSCAFP00000058821 | ENSCAFP00000044202 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Regulator of G protein signaling 6. | 0.561 |
| GNB3 | RGS7 | ENSCAFP00000058821 | ENSCAFP00000023049 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Regulator of G protein signaling 7. | 0.647 |
| GNB3 | RGS7BP | ENSCAFP00000058821 | ENSCAFP00000010809 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Regulator of G protein signaling 7 binding protein. | 0.620 |
| GNB3 | RGS9BP | ENSCAFP00000058821 | ENSCAFP00000011151 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | Regulator of G protein signaling 9 binding protein. | 0.562 |
| GNB5 | CNGB3 | ENSCAFP00000023022 | ENSCAFP00000013075 | G protein subunit beta 5. | Cyclic nucleotide-gated cation channel beta-3; Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses [...] | 0.538 |
| GNB5 | GNB3 | ENSCAFP00000023022 | ENSCAFP00000058821 | G protein subunit beta 5. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.839 |
| GNB5 | LRIT3 | ENSCAFP00000023022 | ENSCAFP00000016927 | G protein subunit beta 5. | Leucine rich repeat, Ig-like and transmembrane domains 3. | 0.561 |
| GNB5 | RGS11 | ENSCAFP00000023022 | ENSCAFP00000060980 | G protein subunit beta 5. | Regulator of G protein signaling 11. | 0.950 |
| GNB5 | RGS6 | ENSCAFP00000023022 | ENSCAFP00000044202 | G protein subunit beta 5. | Regulator of G protein signaling 6. | 0.879 |
| GNB5 | RGS7 | ENSCAFP00000023022 | ENSCAFP00000023049 | G protein subunit beta 5. | Regulator of G protein signaling 7. | 0.879 |