STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM55Tripartite motif containing 55. (550 aa)    
Predicted Functional Partners:
KLHL34
Kelch like family member 34.
   
 
 0.679
USP28
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
   
 
 0.679
KLHL23
Kelch like family member 23.
   
 
 0.654
KLHL38
Kelch like family member 38.
   
 
 0.603
KBTBD12
Kelch repeat and BTB domain containing 12.
   
 
 0.596
ANO5
Anoctamin.
   
  
 0.589
TICAM2
TIR domain-containing protein.
   
 
 0.581
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.566
MYO18B
Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.556
TRIM77
Tripartite motif containing 77.
      
 0.548
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.