STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNKS2Poly [ADP-ribose] polymerase. (1316 aa)    
Predicted Functional Partners:
TNKS
Poly [ADP-ribose] polymerase.
  
0.972
TERF1
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
    
 
 0.964
GMDS
GDP-mannose 4,6-dehydratase.
   
 
 0.920
AXIN1
Axin 1.
    
 0.904
RNF146
Ring finger protein 146.
    
 
 0.902
AXIN2
Axin 2.
    
 0.892
TNKS1BP1
Tankyrase 1 binding protein 1.
    
 
 0.889
LNPEP
Leucyl and cystinyl aminopeptidase.
   
 
 0.876
PARP3
Poly [ADP-ribose] polymerase.
   
 
 0.849
PARP2
Poly [ADP-ribose] polymerase.
   
 
 0.829
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.