KRT81 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KRT81

IF rod domain-containing protein; Belongs to the intermediate filament family. (513 aa)

Predicted Functional Partners:

DSG1

0.863

KRT39

0.765

DSG2

0.763

KRT37

0.734

KRT27

0.731

KRT40

0.715

KRT26

0.707

KRT31

0.705

KRT35

0.701

KRT33B

0.671

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DSG1	DSG2	ENSCAFP00000026689	ENSCAFP00000065154	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Desmoglein-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).	0.961
DSG1	KRT26	ENSCAFP00000026689	ENSCAFP00000023588	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.413
DSG1	KRT27	ENSCAFP00000026689	ENSCAFP00000023584	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.522
DSG1	KRT31	ENSCAFP00000026689	ENSCAFP00000023506	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.440
DSG1	KRT33B	ENSCAFP00000026689	ENSCAFP00000023504	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.408
DSG1	KRT40	ENSCAFP00000026689	ENSCAFP00000023553	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.401
DSG1	KRT81	ENSCAFP00000026689	ENSCAFP00000010849	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.863
DSG2	DSG1	ENSCAFP00000065154	ENSCAFP00000026689	Desmoglein-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.961
DSG2	KRT81	ENSCAFP00000065154	ENSCAFP00000010849	Desmoglein-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.763
KRT26	DSG1	ENSCAFP00000023588	ENSCAFP00000026689	IF rod domain-containing protein; Belongs to the intermediate filament family.	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.413
KRT26	KRT27	ENSCAFP00000023588	ENSCAFP00000023584	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.609
KRT26	KRT31	ENSCAFP00000023588	ENSCAFP00000023506	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.514
KRT26	KRT33B	ENSCAFP00000023588	ENSCAFP00000023504	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.551
KRT26	KRT35	ENSCAFP00000023588	ENSCAFP00000023468	IF rod domain-containing protein; Belongs to the intermediate filament family.	Keratin 35; Belongs to the intermediate filament family.	0.583
KRT26	KRT37	ENSCAFP00000023588	ENSCAFP00000062748	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.521
KRT26	KRT39	ENSCAFP00000023588	ENSCAFP00000030974	IF rod domain-containing protein; Belongs to the intermediate filament family.	Keratin 39; Belongs to the intermediate filament family.	0.586
KRT26	KRT40	ENSCAFP00000023588	ENSCAFP00000023553	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.508
KRT26	KRT81	ENSCAFP00000023588	ENSCAFP00000010849	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.707
KRT27	DSG1	ENSCAFP00000023584	ENSCAFP00000026689	IF rod domain-containing protein; Belongs to the intermediate filament family.	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.522
KRT27	KRT26	ENSCAFP00000023584	ENSCAFP00000023588	IF rod domain-containing protein; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.609