STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
QSER1Glutamine and serine rich 1. (1734 aa)    
Predicted Functional Partners:
PRRG4
Proline rich and Gla domain 4.
 
    
 0.772
CSTF3
Cleavage stimulation factor subunit 3.
   
  
 0.683
DSTYK
Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
   
  
 0.683
GREB1L
GREB1 like retinoic acid receptor coactivator.
      
 0.680
TOPAZ1
Testis and ovary specific PAZ domain containing 1.
      
 0.680
FAXC
Failed axon connections homolog, metaxin like GST domain containing.
      
 0.677
PITPNM2
Phosphatidylinositol transfer protein membrane associated 2.
      
 0.677
KBTBD6
Kelch repeat and BTB domain containing 6.
   
  
 0.674
CWC25
CWC25 spliceosome associated protein homolog.
      
 0.653
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
   
  
 0.642
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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