STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCTD6Potassium channel tetramerization domain containing 6. (237 aa)    
Predicted Functional Partners:
CIT
Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
      
 0.999
SPRYD3
SPRY domain containing 3.
      
 0.979
FBXO45
F-box protein 45.
      
 0.939
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.869
BTBD6
BTB domain containing 6.
    
 0.679
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.677
OPRM1
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.642
KBTBD13
Kelch repeat and BTB domain containing 13.
     
 0.618
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
      
 0.584
KLHL41
Kelch like family member 41.
   
 0.579
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.