STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCL1Achaete-scute family bHLH transcription factor 1. (218 aa)    
Predicted Functional Partners:
DLX2
Distal-less homeobox 2.
   
  
 0.859
MYT1L
Myelin transcription factor 1 like.
   
  
 0.853
OLIG2
Oligodendrocyte transcription factor 2.
   
 
 0.823
SOX10
SRY-box transcription factor 10.
    
 
 0.741
NEUROG1
Neurogenin 1.
   
 
 0.729
NEUROD2
Neurogenic differentiation factor.
  
 
 0.710
TCF4
Transcription factor 4; Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'- CANNTG-3') (By similarity). Binds to the thyroglobulin promoter.
   
 
 0.693
HELT
Helt bHLH transcription factor.
   
 
 0.691
PHOX2A
Paired like homeobox 2A.
   
 
 0.691
TCF12
Transcription factor 12.
   
 
 0.676
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.