STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRRG4Proline rich and Gla domain 4. (225 aa)    
Predicted Functional Partners:
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.803
QSER1
Glutamine and serine rich 1.
 
    
 0.749
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.588
SDR16C5
Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.579
WWTR1
WW domain containing transcription regulator 1.
    
   0.568
YAP1
Yes associated protein 1.
    
   0.568
CEP41
Centrosomal protein 41.
      
 0.519
TAF5
TATA-box binding protein associated factor 5.
      
 0.517
TCP11L1
T-complex 11 like 1.
      
 0.487
TMEM74
Transmembrane protein 74.
      
 0.485
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.