STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPIFA2BPI fold containing family A member 2. (249 aa)    
Predicted Functional Partners:
LOC607055
Fibrinogen C-terminal domain-containing protein.
      
 0.868
MUC19
Uncharacterized protein.
      
 0.861
CA6
Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown (By similarity); Belongs to the alpha-carbonic anhydrase family.
   
  
 0.855
J9NTY3_CANLF
WAP domain-containing protein.
      
 0.830
CHAD
Chondroadherin.
   
  
 0.827
GH1
Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family.
   
    0.825
AMELX
Amelogenin X isoform.
   
    0.824
GHRH
Growth hormone releasing hormone.
   
    0.817
LOC478196
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
    0.817
PRPH2
Peripherin-2; Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). Belongs to the PRPH2/ROM1 family.
   
    0.804
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.