STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGKCImmunoglobulin kappa constant. (113 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
    
   0.719
ENSCAFP00000055032
Ig-like domain-containing protein.
 
     0.552
RD3L
Retinal degeneration 3 like.
      
 0.501
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.
      
 0.489
IGHM
Ig mu chain C region.
  
 
0.462
UBB
Ubiquitin B.
    
 
 0.447
J9P0D4_CANLF
Ig-like domain-containing protein.
 
     0.444
HSPA2
Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family.
      
 0.420
E2QXJ3_CANLF
Ig-like domain-containing protein.
 
     0.419
F1PP29_CANLF
Uncharacterized protein.
   
   0.418
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.