STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF143Zinc finger protein 143. (637 aa)    
Predicted Functional Partners:
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 
 0.825
SP1
Sp1 transcription factor.
   
 
0.812
POU2F1
POU domain protein.
   
  0.805
AK6
Uncharacterized protein.
   
 0.768
GTF2A2
General transcription factor IIA subunit 2.
   
 
 0.749
RAD21
RAD21 cohesin complex component.
   
 
 0.723
HSPBP1
HSPA (Hsp70) binding protein 1.
   
 
 0.670
TBP
TATA-box binding protein.
   
 0.650
RCOR2
REST corepressor 2.
    
 
 0.647
GTF2B
General transcription factor IIB.
   
 0.646
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.