STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM23Tripartite motif containing 23. (574 aa)    
Predicted Functional Partners:
RPS27A
Ubiquitin-like domain-containing protein.
   
 
 0.893
ENSCAFP00000050780
Ubiquitin-like domain-containing protein.
   
 
 0.892
UBA52
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]
   
 
 0.842
ENSCAFP00000058401
annotation not available
   
 
 0.841
ENSCAFP00000063070
Ubiquitin-like domain-containing protein.
   
 
 0.841
PPWD1
Peptidylprolyl isomerase domain and WD repeat containing 1.
   
  
 0.808
TRIM44
Tripartite motif containing 44.
   
 
 0.771
CENPK
Centromere protein K.
   
  
 0.770
TRIM54
Tripartite motif containing 54.
   
 
 0.737
NME8
NME/NM23 family member 8.
   
 
 0.734
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.