| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSCAFP00000051572 | ENSCAFP00000058057 | ENSCAFP00000051572 | ENSCAFP00000058057 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Sm domain-containing protein. | 0.707 |
| ENSCAFP00000051572 | KMT5A | ENSCAFP00000051572 | ENSCAFP00000011111 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Lysine methyltransferase 5A. | 0.881 |
| ENSCAFP00000051572 | RBM41 | ENSCAFP00000051572 | ENSCAFP00000044281 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | RNA binding motif protein 41. | 0.507 |
| ENSCAFP00000051572 | RNPC3 | ENSCAFP00000051572 | ENSCAFP00000029595 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | RNA binding region (RNP1, RRM) containing 3. | 0.742 |
| ENSCAFP00000051572 | SF3B2 | ENSCAFP00000051572 | ENSCAFP00000019222 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Splicing factor 3b subunit 2. | 0.900 |
| ENSCAFP00000051572 | SNRNP25 | ENSCAFP00000051572 | ENSCAFP00000037695 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Small nuclear ribonucleoprotein U11/U12 subunit 25. | 0.500 |
| ENSCAFP00000051572 | SNRNP48 | ENSCAFP00000051572 | ENSCAFP00000014074 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Small nuclear ribonucleoprotein U11/U12 subunit 48. | 0.808 |
| ENSCAFP00000051572 | SNRPD1 | ENSCAFP00000051572 | ENSCAFP00000026957 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. | 0.920 |
| ENSCAFP00000051572 | SRSF1 | ENSCAFP00000051572 | ENSCAFP00000025697 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Serine and arginine rich splicing factor 1. | 0.817 |
| ENSCAFP00000051572 | ZCRB1 | ENSCAFP00000051572 | ENSCAFP00000038540 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Zinc finger CCHC-type and RNA binding motif containing 1. | 0.631 |
| ENSCAFP00000058057 | ENSCAFP00000051572 | ENSCAFP00000058057 | ENSCAFP00000051572 | Sm domain-containing protein. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.707 |
| ENSCAFP00000058057 | KMT5A | ENSCAFP00000058057 | ENSCAFP00000011111 | Sm domain-containing protein. | Lysine methyltransferase 5A. | 0.960 |
| ENSCAFP00000058057 | RBM41 | ENSCAFP00000058057 | ENSCAFP00000044281 | Sm domain-containing protein. | RNA binding motif protein 41. | 0.943 |
| ENSCAFP00000058057 | RNPC3 | ENSCAFP00000058057 | ENSCAFP00000029595 | Sm domain-containing protein. | RNA binding region (RNP1, RRM) containing 3. | 0.946 |
| ENSCAFP00000058057 | SF3B2 | ENSCAFP00000058057 | ENSCAFP00000019222 | Sm domain-containing protein. | Splicing factor 3b subunit 2. | 0.966 |
| ENSCAFP00000058057 | SNRNP25 | ENSCAFP00000058057 | ENSCAFP00000037695 | Sm domain-containing protein. | Small nuclear ribonucleoprotein U11/U12 subunit 25. | 0.900 |
| ENSCAFP00000058057 | SNRNP48 | ENSCAFP00000058057 | ENSCAFP00000014074 | Sm domain-containing protein. | Small nuclear ribonucleoprotein U11/U12 subunit 48. | 0.947 |
| ENSCAFP00000058057 | SNRPD1 | ENSCAFP00000058057 | ENSCAFP00000026957 | Sm domain-containing protein. | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. | 0.997 |
| ENSCAFP00000058057 | SRSF1 | ENSCAFP00000058057 | ENSCAFP00000025697 | Sm domain-containing protein. | Serine and arginine rich splicing factor 1. | 0.551 |
| ENSCAFP00000058057 | ZCRB1 | ENSCAFP00000058057 | ENSCAFP00000038540 | Sm domain-containing protein. | Zinc finger CCHC-type and RNA binding motif containing 1. | 0.918 |