STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD27Ankyrin repeat domain 27. (978 aa)    
Predicted Functional Partners:
AP3D1
Adaptor related protein complex 3 subunit delta 1.
    
 
 0.869
RAB32
RAB32, member RAS oncogene family.
    
 
 0.862
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.859
CSNK2A2
Casein kinase 2 alpha 2.
   
 0.832
RAB38
RAB38, member RAS oncogene family.
    
 
 0.732
UBXN11
UBX domain protein 11.
    
 
 0.701
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.658
ENSCAFP00000047301
Uncharacterized protein.
    
 
 0.658
NFKBIA
NFKB inhibitor alpha.
    
 
 0.589
VTI1B
Vesicle transport through interaction with t-SNAREs 1B.
    
 
 0.573
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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