STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IMMTMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (788 aa)    
Predicted Functional Partners:
SAMM50
SAMM50 sorting and assembly machinery component.
   
 
 0.951
CHCHD3
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
 
 0.928
MTX2
Metaxin 2.
   
 
 0.907
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family.
   
 
 0.822
DNAJC11
DnaJ heat shock protein family (Hsp40) member C11.
   
 
 0.818
ECPAS
Ecm29 proteasome adaptor and scaffold.
   
  
 0.800
J9NYN5_CANLF
MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.779
ENSCAFP00000054080
MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.779
COX15
Cytochrome c oxidase assembly homolog COX15.
   
 
 0.756
APOOL
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.756
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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