STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (465 aa)    
Predicted Functional Partners:
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.
      
 0.830
KCNN1
Potassium calcium-activated channel subfamily N member 1.
      
 0.595
FBXW9
F-box and WD repeat domain containing 9.
    
 
 0.593
FSCN1
Fascin actin-bundling protein 1.
      
 0.593
NKAIN1
Sodium/potassium transporting ATPase interacting 1.
      
 0.591
TMEM89
Transmembrane protein 89.
      
 0.591
ANKRD33B
Ankyrin repeat domain 33B.
      
 0.533
GADD45B
Growth arrest and DNA damage inducible beta.
      
 0.489
TNFSF10
Tumor necrosis factor ligand superfamily member.
      
 0.482
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
      
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.