STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)    
Predicted Functional Partners:
NWD2
NACHT and WD repeat domain containing 2.
      
 0.811
RIMS4
Regulating synaptic membrane exocytosis 4.
      
 0.810
WDR93
WD repeat domain 93.
      
 0.803
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.742
CUL5
Cullin 5; Belongs to the cullin family.
    
 
 0.727
SPSB3
SplA/ryanodine receptor domain and SOCS box containing 3.
     
 0.716
RHOBTB1
Rho related BTB domain containing 1.
      
 0.700
ELOB
Elongin B.
    
 0.689
ARHGEF19
Rho guanine nucleotide exchange factor 19.
      
 0.674
NOSIP
Nitric oxide synthase interacting protein.
   
  
 0.666
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.