STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM111BFamily with sequence similarity 111 member B. (734 aa)    
Predicted Functional Partners:
ZDBF2
Zinc finger DBF-type containing 2.
   
  
 0.790
CCDC73
Coiled-coil domain containing 73.
      
 0.714
NKTR
Natural killer cell triggering receptor.
      
 0.674
SYCP1
Synaptonemal complex protein 1.
   
  
 0.667
JPH4
Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
    
 
 0.663
CDCP2
CUB domain containing protein 2.
      
 0.649
RBM10
RNA binding motif protein 10.
      
 0.643
SCLT1
Sodium channel and clathrin linker 1.
   
  
 0.642
OSTF1
Osteoclast stimulating factor 1.
      
 0.619
PKHD1L1
PKHD1 like 1.
      
 0.598
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.