STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYBG3Crystallin beta-gamma domain containing 3; Belongs to the beta/gamma-crystallin family. (3091 aa)    
Predicted Functional Partners:
CUEDC2
CUE domain containing 2.
      
 0.848
DAB2IP
DAB2 interacting protein.
      
 0.701
PTTG1
Uncharacterized protein.
      
 0.573
ARL6
ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family.
 
  
   0.548
MCC
MCC regulator of WNT signaling pathway.
   
  
 0.472
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 
 0.470
ANAPC15
Anaphase promoting complex subunit 15.
      
 0.440
PLK1
Serine/threonine-protein kinase PLK.
   
  
 0.429
CDC27
Cell division cycle 27.
   
  
 0.414
CRYZL1
PKS_ER domain-containing protein.
   
  
 0.414
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.