STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF7Ring finger protein 7. (90 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.998
ELOB
Elongin B.
   
 0.990
ELOC
Elongin C; Belongs to the SKP1 family.
   
 0.954
CUL2
Cullin 2; Belongs to the cullin family.
   
 0.934
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.909
UBE2F
Ubiquitin conjugating enzyme E2 F (putative); Belongs to the ubiquitin-conjugating enzyme family.
   
 0.909
UBE2D1
Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.838
ARIH2
RBR-type E3 ubiquitin transferase.
   
 
 0.824
DDB1
Damage specific DNA binding protein 1.
    
 
 0.803
CAND1
Cullin associated and neddylation dissociated 1.
    
 0.790
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.