Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RIOK2RIO kinase 2. (548 aa)    
Predicted Functional Partners:
RIOK3
Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.
   
 0.993
LTV1
LTV1 ribosome biogenesis factor.
   
 0.992
BYSL
Bystin like.
   
 0.990
NOB1
RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family.
   
 0.988
RIOK1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
0.981
NOP9
NOP9 nucleolar protein.
   
 
  0.933
KRR1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.909
ENSCAFP00000063758
RIO domain-containing protein.
  
  
 
0.900
RRP12
Ribosomal RNA processing 12 homolog.
   
 
 0.884
PNO1
Partner of NOB1 homolog.
   
 
 0.835
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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