STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND6ADENN domain containing 6A. (608 aa)    
Predicted Functional Partners:
SUOX
Sulfite oxidase.
     
  0.801
DENND11
KIAA1147.
      
 0.681
DENND10
Family with sequence similarity 45 member A.
      
 0.677
AVL9
AVL9 cell migration associated.
      
 0.662
TBC1D10B
TBC1 domain family member 10B.
    
 
 0.662
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
     
  0.605
RELCH
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing.
    
   0.573
TBC1D10A
TBC1 domain family member 10A.
    
 
 0.563
PRKCSH
Protein kinase C substrate 80K-H.
    
   0.557
DENND4C
DENN domain containing 4C.
      
 0.522
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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