STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM184CTransmembrane protein 184C. (481 aa)    
Predicted Functional Partners:
FAM204A
Family with sequence similarity 204 member A.
   
  
 0.861
HSF2
Heat shock transcription factor 2.
   
  
 0.844
RAB11FIP2
RAB11 family interacting protein 2.
   
 
 0.722
PRMT9
Protein arginine methyltransferase 9; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
   
  
 0.713
EDNRA
Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity).
      
 0.692
FADS6
Fatty acid desaturase 6.
      
 0.664
PYROXD1
Pyridine nucleotide-disulphide oxidoreductase domain 1.
      
 0.606
TMEM207
Transmembrane protein 207.
   
  
 0.550
VEZT
Vezatin, adherens junctions transmembrane protein.
   
  
 0.542
EXOC3L4
Exocyst complex component 3 like 4.
   
  
 0.537
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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